Bileacids相关论文
Understanding the physiological functions of the host xenobiotic-sensing nuclear receptors PXR and C
Pharmacological activation of the xenobiotic-sensing nuclear receptors pregnane X receptor(PXR)and constitutive androsta......
TGR5 deficiency activates antitumor immunity in non-small cell lung cancer via restraining M2 macrop
The bile acid-responsive G-protein-coupled receptor TGR5 is expressed in monocytes and macrophages,and plays a critical ......
Bile acids(BAs)are amphipathic molecules important for metabolism of cholesterol,absorp-tion of lipids and lipid soluble......
Metabolic profiling of endogenous bile acids:a novel method to assess hepatoprotective effect of Tan
Tanreqing (TRQ),a traditional Chinese medicine (TCM) formula,can alleviate liver injury and improve liver function.Its p......
Development of a LC-MS/MS method for simultaneous determination of bile acids and their conjugates i
It is still uncertain whether the accumulation of the Bas in hepatocytes beyond the normal stand after taking medicine w......
Effect of cholecystectomy on bile acids, enzymes and transporters in mice:Implications for pharmacok
Cholecystectomy is a traditional and effective therapeutic tool for hepatobiliary diseases whose morbidity has increased......
Sweroside ameliorates α-naphthylisothiocyanate induced cholestatic liver injury through bile acid re
Aim: Sweroside, an iridoid glycoside, exerts diverse biological activities.The study aimed to investigate how sweroside ......
Bile acids as Novel Indicator of Hepatocellular Carcinoma:Small-Molecule Markers Screening from Bile
The identification of a sensitive and specific serum marker will facilitate the early diagnosis ofhepatocellular carcino......
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Notoginsenoside Ft1 acts as a TGR5 agonist but FXR antagonist to alleviate high fat diet-induced obe
Obesity and its associated complications are highly related to a current public health crisis around the world.A growing......
胆汁酸由胆固醇在肝内合成,是胆汁的主要有机成分。以往对胆汁酸功能的认识主要是其在促进脂类营养物质的消化和吸收方面的作用。近......
Differential expression of cholangiocyte and ileal bile acid transporters following bile acid supple
AIM: We have previously demonstrated that cholangiocytes,the epithelial cells lining intrahepatic bile ducts, encode two......
AIM: To develop a new experimental model of esophagitis that serves a complementary tool to clinical investigation in an......
Bile acids are not only important for the absorption of dietary lipids and fat soluble vitamins but are signalling molec......